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KMID : 0357520140370040279
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Journal of Radiological Science and Technology
2014 Volume.37 No. 4 p.279 ~ p.286
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An Analysis of BMD Changes With Preoperative and Postoperative Premenopausal Breast Cancer Patient
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Kim Su-Jin
Son Soon-Yong
Choi Kwan-Woo
Lee Joo-Ah
Min Jung-Whan
Kim Hyun-Soo
Ma Sang-Chul
Yoo Beong-Gyu
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Abstract
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The purpose of this study is to provide basic data of comparing BMD(bone mineral density) value of preoperative breast cancer patient and postoperative breast cancer patient due to bone loss with radiation/chemical therapy. The participants consisted of 254 breast cancer patients with BMD after having surgery and treatment from March 2007 to September 2013. Except for 84 patients with menopause or hysterectomy and we have analysed 171 patients. The BMD value(lumbar spine and femur) of before and after treatment from PACS by dure-energy X-ray absorptiometry was analyzed. First, we found variation of entire BMD and BMD according to treatment type, and analyzed detailed correlation by using marital status,
number of children, presence of feeding, age of menarche, breast cancer therapy types as variable. Data was analyzed by using SPSS for Windows Program(version 18.0). BMD was decreased 7.1% in lumbar spine, 3.1% in femur respectively(p<.01). Also there is relatively high decrement(0.067 g/cm2 ) in group who had just chemotherapy in femur(p<.05). There is decrement depend on marital status, number of children, presence of feeding, age of menarche, breast cancer therapy types but there was no statistical significance. The results show that BMD was decreased after treatment in premenopausal breast cancer patient, patient who had relatively high decrement need to be included high-risk group. As a result, aggressive prevention policy would be necessary.
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KEYWORD
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Breast Cancer, BMD (Bone Mineral Density), high-risk group
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